For the setting up or relocating of bees, the following rules apply: the best time is on a waxing moon, but not in Cancer or Leo. Another ineffective time is on a waning moon. For cleaning the beehive, the best time is in a waning moon. The bees will stay calm and be less aggressive. Furthermore the outbreak of diseases will be less likely. If you choose the wrong time for the relocation, it's possible that the bees will not accept the new beehive.